The definitive diagnosis of ectopic pregnancy can be made with ultrasound visualization of a yolk sac and or embryo in the adnexa hillson c diagnosis and management of ectopic pregnancy . Ectopic pregnancy should be considered in any patient presenting early in pregnancy with vaginal bleeding or lower abdominal pain in whom intrauterine pregnancy has not yet been established the definitive diagnosis of ectopic pregnancy can be made with ultrasound visualization of a yolk sac and or embryo in the adnexa. The incidence of ectopic pregnancy is increasing in 1992 the rate of ectopic pregnancies was 197 per 1000 in the usa which was an increase from 45 per 1000 in 1970 this increase may be associated with an increase in the prevalence of risk factors for ectopic pregnancy such as pelvic infections. Ectopic pregnancy diagnosis and management kulp jl1 barnhart kt author information 1university of pennsylvania medical center penn fertility care department of obstetrics and gynecology 3701 market st suite 810 philadelphia pa 19104 usa